Context-Aware Aided Parking Solutions Based on VANET

Vehicular Ad-hoc Network (VANET) is a special application of the Mobile Ad-hoc Network (MANET) for managing road traffic and substantially contributes to the development of Intelligent Transportation Systems (ITS). VANET was introduced as a standard for data communication between moving vehicles with and without fixed infrastructure. It aims to support drivers by improving safety and driving comfort as a step towards constructing a safer, cleaner and a more intelligent environment. Nowadays, vehicles are manufactured equipped with a number of sensors and devices called On Board Units (OBU) assisting the vehicle to sense the surrounding environment and then process the context information to effectively manage communication with the surrounding vehicles and the associated infrastructure. A number of challenges have emerged in VANET that have encouraged researchers to investigate this concept further. Many of the recent studies have applied different technologies for intelligent parking management. However, despite all the technological advances, researchers are no closer to developing a system that enables drivers to easily locate and reserve a parking space. Limited resources such as energy, storage space, availability and reliability are factors which could have contributed to the lack success and progress in this area. The task then is to close these gaps and present a novel solution for parking.This research intends to address this need by developing a novel architecture for locating and reserving a parking space that best matches the driver's preferences and vehicle profile without distracting the driver. The simple and easy-to-use mechanism focuses on the domain of an intelligent parking system that exploits the concept of InfoStation (IS) and context-aware system creating a single framework to locate and reserve a parking space. A three tier network topology comprising of vehicles, IS and the InfoStation Centre (ISC) has been proposed as the foundation of the on-street parking system architecture. The thesis attempts to develop the architecture of a parking management solution as a comfort-enhancing application that offers to reduce congestion related stress and improve the driver experience by reducing the time it takes to identify and utilise a parking space that is available.Saudi Arabia Cultural Bureau in U

Langerhans cell histiocytosis presenting as a blueberry muffin rash

Langerhans cells, often referred to as the “macrophages of the skin”, are dendritic cells that normally reside in the epidermis and papillary dermis. Just like macrophages, they function as antigen-presenting cells that activate naive T cells. Certain mutations such as those involving the BRAF gene can cause unopposed production of Langerhans Cells, which is known as Langerhans Cell Histiocytosis (LCH). LCH triggers an inflammatory immune response that causes systemic manifestations such as fever and fatigue, as well as other manifestations depending on the affected organs. The pathogenesis behind LCH remains poorly understood. It is still unknown whether it is a neoplastic process or a reactive cancer-mimicking illness. Diagnosis of LCH is confirmed by biopsy, and treatment is largely dependent on the extent and severity of the disease. Common treatments include corticosteroids, excision, radiation, and chemotherapy. We present a case of a 1-year-old Saudi male with LCH

SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study

Background: Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods: The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV estimates were stratified by age (18-49, 50-69, 70 or more years) and type of surgery. Best- and worst-case scenarios were used to describe uncertainty. Results: NNVs were more favourable in surgical patients than the general population. The most favourable NNVs were in patients aged 70 years or more needing cancer surgery (351; best case 196, worst case 816) or non-cancer surgery (733; best case 407, worst case 1664). Both exceeded the NNV in the general population (1840; best case 1196, worst case 3066). NNVs for surgical patients remained favourable at a range of SARS-CoV-2 incidence rates in sensitivity analysis modelling. Globally, prioritizing preoperative vaccination of patients needing elective surgery ahead of the general population could prevent an additional 58 687 (best case 115 007, worst case 20 177) COVID-19-related deaths in 1 year. Conclusion: As global roll out of SARS-CoV-2 vaccination proceeds, patients needing elective surgery should be prioritized ahead of the general population